Levitra

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Levitra (vardenafil) relaxes muscles found in the walls of blood vessels and increases blood flow to particular areas of the body.

Levitra is used to treat erectile dysfunction (impotence).

Levitra may also be used for purposes not listed in this medication guide.

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HOW SHOULD I TAKE LEVITRA?

Levitra can be taken with or without food.

Levitra is usually taken only when needed, about 60 minutes before sexual activity. The medicine can help achieve an erection when sexual stimulation occurs. An erection will not occur just by taking a pill. Do not take this medicine more than once a day. Allow 24 hours to pass between doses.

BEFORE TAKING THIS MEDICINE

You should not use Levitra if you are allergic to vardenafil.

Taking Levitra with certain other medicines can cause a sudden and serious decrease in blood pressure. Do not take vardenafil if you also take riociguat (Adempas), or if you take a nitrate drug for chest pain or heart problems. Nitrates include nitroglycerin, isosorbide dinitrate, and isosorbide mononitrate. Nitrates are also found in some recreational drugs such as amyl nitrate or nitrite (“poppers”).

To make sure Levitra is safe for you, tell your doctor if you have:

  • heart disease, heart rhythm problems;
  • a recent history (in the past 6 months) of a heart attack, stroke, or congestive heart failure;
  • a personal or family history of Long QT syndrome;
  • high or low blood pressure;
  • seizures;
  • liver disease, kidney disease (or if you are on dialysis);
  • a blood cell disorder such as sickle cell anemia, multiple myeloma, or leukemia;
  • a bleeding disorder such as hemophilia;
  • a stomach ulcer;
  • hearing or vision problems, history of vision loss;
  • an eye disorder such as retinitis pigmentosa (an inherited condition of the eye);
  • a physical deformity of the penis (such as Peyronie’s disease); or
  • if you have been told you should not have sexual intercourse for health reasons.

Levitra can decrease blood flow to the optic nerve of the eye, causing sudden vision loss. This has occurred in a small number of people taking Viagra or other drugs similar to vardenafil. Most of these people also had certain pre-existing eye problems or risk factors for blood vessel disorders (such as heart disease, diabetes, high blood pressure, high cholesterol, coronary artery disease, smoking, or being over 50 years old). It is not clear whether vardenafil is the actual cause of vision loss.

Although Levitra is not for use in women, it is not known whether this medicine passes into breast milk or if it could harm a nursing baby.

Contact your doctor or seek emergency medical attention if your erection is painful or lasts longer than 4 hours. A prolonged erection (priapism) can damage the penis.

Store at room temperature away from moisture and heat.

LEVITRA DOSING INFORMATION

Usual Adult Dose for Erectile Dysfunction:

-Initial dose: 10 mg orally once a day, as needed, approximately 60 minutes before sexual activity. Increase to 20 mg or decrease to 5 mg based on efficacy and tolerability.
-Maximum dose: 20 mg once a day

Patients on stable alpha blocker therapy:
-Initial dose: 5 mg orally once a day

Comments:
-Sexual stimulation is required for a response to treatment.
-A time interval between dosing should be considered when administering this drug concomitantly with alpha-blockers.

Use: Erectile dysfunction

Usual Geriatric Dose for Erectile Dysfunction:

65 years or older:
-Initial dose: 5 mg orally once a day, as needed, approximately 60 minutes before sexual activity

Comments: Sexual stimulation is required for a response to treatment.

Use: Erectile dysfunction

WHAT HAPPENS IF I MISS A DOSE?

Since Levitra is used as needed, you are not likely to be on a dosing schedule.

WHAT HAPPENS IF I OVERDOSE?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

WHAT SHOULD I AVOID WHILE TAKING LEVITRA?

Grapefruit and grapefruit juice may interact with vardenafil and lead to unwanted side effects. Avoid the use of grapefruit products while taking vardenafil.

Drinking alcohol can increase certain side effects of Levitra.

Do not use any other drug to treat impotence unless your doctor tells you to.

WHAT OTHER DRUGS WILL AFFECT LEVITRA?

Do not take Levitra with similar medicines such as avanafil (Stendra), sildenafil (Viagra), or tadalafil (Cialis). These medicines also have other brand names (Adcirca, Revatio) that are used to treat a condition called pulmonary arterial hypertension.

Tell your doctor about all medicines you use, and those you start or stop using during your treatment with Levitra, especially:

  • all other medications you use for erectile dysfunction;
  • an antibiotic – clarithromycin, erythromycin, telithromycin, and others;
  • antifungal medicine – itraconazole, ketoconazole, and others;
  • drugs to treat high blood pressure or a prostate disorder – alfuzosin, doxazosin, prazosin, silodosin, terazosin, tamsulosin;
  • heart rhythm medicine – amiodarone, dofetilide, disopyramide, dronedarone, procainamide, quinidine, sotalol; or
  • HIV/AIDS medicine – atazanavir, indinavir, ritonavir, saquinavir, and others.
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